Principal Investigators
Dr. Lane is a Senior Scientist in the Department of Basic and Translational Research at the BC Cancer Research Institute. His formal training includes a BEngMgt (Engineering Physics and Management) from McMaster University (1993), an MASc (Electrical Engineering) from the Technical University of Nova Scotia (1996), and a PhD (Electrical and Computer Engineering) from Dalhousie University (1999). He is an Associate Professor of Practice in the School of Engineering Science at Simon Fraser University (SFU), and an Affiliate Associate Professor in the School of Biomedical Engineering at the University of British Columbia.
Dr. Lane is interested in the in vivo application of optical imaging, tissue optics, and spectroscopy for the early detection, diagnosis, and management of cancer. He develops and evaluates new optical tools to address unmet clinical needs and works closely with clinical collaborators to evaluate and test these tools in a clinical context. These tools include instrumentation, software, computer algorithms, systems and devices that can be used clinically or in a laboratory to measure the structural, morphological, functional, biochemical or molecular characteristics of tissue.
Dr. MacAulay is the Head of Integrative Oncology at the BCCRC. His formal training includes a BSc in Engineering Physics (1982) from Dalhousie University, an MSc in Physics (1985) from Dalhousie University, and a PhD in Physics (1989) from the University of British Columbia. Dr. MacAulay is an Associate Member of the Department of Physics and Astronomy and a Clinical Associate Professor in the Department of Pathology at the University of British Columbia.
Dr. MacAulay’s research focuses on the development of clinical tools for the detection, grading, and treatment of early, non-invasive cancer. It has long been recognized that cancer can be successfully treated at an early stage, including cancer of the lung, breast, cervix, colon and prostate. Dr. MacAulay’s work includes the development of both macroscopic and microscopic optical imaging devices, image analysis and automated assessment, artificial intelligence, and clinical translation of these technologies.
Staff
Sylvia Lam
Research Assistant
sflam@bccrc.ca
Sylvia has a Bachelor of Science (BSc) in Molecular Biology and Biochemistry from Simon Fraser University (SFU) and is also a graduate of the Biomedical Engineering program at the British Columbia Institute of Technology (BCIT). Sylvia is the go-to person in the lab and clinic. She coordinates applications to the Research Ethics Board for new studies.
Post-Doctoral Fellows
Adrian has a doctorate from UBC in Biomedical Engineering, and a BASc (SFU Engineering Physics). He is interested in advancing the state-of-the art in multimodal endoscopic imaging, in particular, the effective combination of OCT and low NA modalities (such as autofluorescence, fluorescence lifetime, and/or reflectance). Adrian’s work seeks to explore the multipath artifacts present in double clad fiber and develop techniques to improve image quality in multimodal single fiber probes.
Select Publications
- Multipath artifacts enable angular contrast in multimodal endoscopic optical coherence tomography
- Triple-clad W-type fiber mitigates multipath artifacts in multimodal optical coherence tomography
- Higher-Order Core-Like Modes in Double-Clad Fiber Contribute to Multipath Artifacts in Optical Coherence Tomography
Jeanie has a doctorate from UBC in Biomedical Engineering, and a BASc (UBC Electrical Engineering). Her work focuses on clinical translation: she is exploring the utility of endoscopic OCT and OCT-AFI for gynaecologic cancer detection and management. Jeanie is currently leading clinical studies imaging the fallopian tubes in the operating room in late stage cancer patients.
Select Publications
- Multimodal Optical Imaging of Ex Vivo Fallopian Tubes to Distinguish Early and Occult Tubo-Ovarian Cancers
- Multipath artifacts enable angular contrast in multimodal endoscopic optical coherence tomography
- Imaging Biomarkers of Oral Dysplasia and Carcinoma Measured with In Vivo Endoscopic Optical Coherence Tomography
Graduate Students
Eric Brace
PhD Student, Engineering Science – Interdisciplinary Oncology Graduate Specialization (SFU)
Eric holds Bachelor of Applied Science and Master of Applied Science degrees in Mechanical Engineering from the University of Waterloo. Eric is developing imaging tools for biopsy guidance and surgical margin detection of oral cancer. This includes the development of micromotor-based imaging probes, angiography algorithms, and a new imaging platform.
Select Publications
Ian holds a BSc in physics from UBC, and his background is in medical physics. His work is focused on lung cancer management using computer vision tools and artificial intelligence.
Select Publications
- Machine Learning and Computed Tomography Radiomics to Predict Disease Progression to Upfront Pembrolizumab Monotherapy in Advanced Non-Small-Cell Lung Cancer: A Pilot Study
- Tensor Radiomics: Paradigm for Systematic Incorporation of Multi-Flavoured Radiomics Features
- Prediction of Disease Progression to Upfront Pembrolizumab Monotherapy in Advanced Non-Small-Cell Lung Cancer with High PD-L1 Expression Using Baseline CT Disease Quantification and Smoking Pack Years
Kimiya Mousavi
MASc Student, Biomedical Engineering (UBC)
kmousavi@bccrc.ca
Kimiya graduated with a Bachelor of Engineering in Biomedical Engineering from UVic. Her work focuses on using OCT on a microscopic scale to dynamically image tissue with the goal of detecting individual cells with increased contrast. This includes developing a microscopic OCT system and dynamic image processing software.
Fumi graduated from UBC with a Bachelor’s in Medical Laboratory Sciences. His work focuses on quantitative analysis of tissue sections, specifically leveraging machine learning to analyze individual cells, interactions and spatial organization to understand cancer progression.
Shahed holds a Bachelor of Applied Science in Mechatronic Systems Engineering from SFU. His work focuses on the design of optical tools for photodynamic therapy and their integration into clinical applications.
Alumni
Co-ops, Summer Students & Undergrad Theses
Rachel Chao, Co-op Student
Ian Wang, Co-op Student
Alicia Fung, Co-op Student
Shahed Ejadi, Co-op Student
Allan Zuckermann Cynamon, Undergraduate Thesis
Mehar Rehill, Undergraduate Thesis
Alicia Fung, Co-op Student
Sophie Kenny, Co-op Student
Malcolm Brown, Undergraduate Thesis & Research Engineer
Andrea Manjarres, Co-op Student & Undergraduate Thesis
Oleksii (Alex) Proskurin, Co-op Student
Ian Thompson, Co-op Student
Carley Schwartz, Co-op Student
Elizabeth Wicks, Co-op Student
Riley Marsh, Co-op Student
Adrian Tanskanen, Co-op Student
Patricia Angkiriwang, Co-op Student
Ryan Goldan, Co-op Student & Undergraduate Thesis
Lucas Cahill, Co-op Student & Undergraduate Thesis
Joel McFaul, Co-op Student
Michelle Cua, Co-op Student
Larix Lee, Co-op Student
Michael Yalowsky, Co-op Student
Brian McFadden, Co-op Student
Greg Dennis, Co-op Student
Ricky Lo, Co-op Student
Siebren Kwekkeboom, Co-op Student
Eric Finlay, Co-op Student
Investigators, Post-Doctoral Fellows & Staff
Geoffrey Hohert, Research Engineer
Dr. Anthony Lee, Staff Scientist
Andrea (Andie) Buenconsejo, Research Assistant
Reid Tingley, Research Assistant
Dr. Hamid Pahlevaninezhad, Post-Doctoral Fellow
Colin Schlosser, Research Engineer
Soufiane El Hallani, Research Fellow
Mark Cardeno, Research Technologist
Sujin Lee, Graduate Student Collaborator
Jinbiao Xu, Programmer
Nasir Zulkafly, Research Engineer
Daryl Hyun, Research Assistant
Jamie Cole, Programmer
Dr. Anders Ballestad, Post-Doctoral Fellow